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Volume of distribution6/14/2023 ![]() The apparent volume of distribution ( V d) is an important pharmacokinetic parameter that relates drug plasma concentrations to the amount of drug in the body and is important for drug loading dose and maintenance dose calculations. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. There was no additional external funding received for this study. J2012-114),, and the College of Medicine of the University of Saskatchewan. Russell at This work was supported by the Sylvia Fedoruk Canadian Centre for Nuclear Innovation (grant no. ![]() This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: The third party data is available from Dr. Received: FebruAccepted: JPublished: July 12, 2016Ĭopyright: © 2016 Wesolowski et al. PLoS ONE 11(7):Įditor: Damir Janigro, Cleveland Clinic, UNITED STATES ![]() Citation: Wesolowski CA, Wesolowski MJ, Babyn PS, Wanasundara SN (2016) Time Varying Apparent Volume of Distribution and Drug Half-Lives Following Intravenous Bolus Injections.
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